The Blackhawk Museum is best known for its significant collection of classic, rare and unique automobiles. It houses about 90 classic cars and a display showcasing the work of the Wheelchair Foundation. One of the museum's most unusual features is a 1924 Hispano-Suiza H6C with a body paneled with tulipwood. Over the years, the museum has also housed a 1962 John F. Kennedy limousine and a Chinese Hongqi, the first Chinese made automobile to be imported to the United States.
In February 2015, the museum added a permanent collection of 19th century North American artifacts called The Spirit of the Old West, showcasing both the settler and Native American stories of the European expansion of North America in the 1800s. The facility is located within the Blackhawk Plaza shopping center, and is an affiliate through the Smithsonian Affiliations program.